Prognostic value of pretreatment peripheral blood biomarkers in patients with head and neck squamous cell carcinoma treated with chemo/bioradiotherapy.

ABSTRACT:

Purpose

Hematological parameters obtained from a pretreatment peripheral blood lab test, as well as indices calculated from these parameters, are associated with the prognosis of the disease in patients with head and neck squamous cell carcinomas (HNSCC). The aim of this study is to determine which of the parameters or indices would have the best prognostic ability in HNSCC patients treated with chemo-radiotherapy or bio-radiotherapy.

Methods/patients

Retrospective study of 345 patients with HNSCC treated with chemo/bio-radiotherapy, for whom a pretreatment lab test was available.

Results

Of the parameters and indices analyzed, the one with the best prognostic capacity was the Host-index (H-index), which combines the prognostic capacity of hemoglobin and albumin level

SUBMITTER: Sansa A 

PROVIDER: S-EPMC12559090 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature