Sublobar Resection in Stage I Lung Cancer With Tumor Spread Through Air Spaces.

ABSTRACT:

Background

Stage I lung cancer is increasingly being treated with sublobar resection. However, it is unknown whether patients with airspace invasion derive similar benefits. We therefore analyzed the association between tumor spread through air spaces (STAS) and survival.

Methods

A retrospective cohort analysis was conducted on 421 patients who underwent a lung cancer resection between 2018 and 2022 at an academic institution. Baseline characteristics were compared between patients who did and did not have STAS. Overall survival and disease recurrence were analyzed using Kaplan-Meier and Cox models.

Results

Of 421 patients who underwent lung cancer resection, 97 (23%) had STAS. There was no difference in STAS based on comorbidities or pulmonary function, however, pati

SUBMITTER: Axtell AL 

PROVIDER: S-EPMC12559274 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature