Hyperuricemia is associated with altered perioperative neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and inflammatory responses in patients residing in high-altitude regions who underwent anterior cruciate ligament reconstruction: A cross-sectional study.

ABSTRACT: ObjectiveHyperuricemia is a common metabolic disorder linked to systemic inflammation; however, its impact on perioperative hematological and inflammatory markers in patients residing in high-altitude regions who have undergone anterior cruciate ligament reconstruction remains unclear. We hypothesized that hyperuricemia is associated with a heightened perioperative inflammatory response.MethodsThis retrospective, cross-sectional study included 83 long-term high-altitude (≥2500 m) residents who underwent anterior cruciate ligament reconstruction between 2019 and 2025. Patients were divided into hyperuricemia (n = 40) and normouricemia (n = 43) groups based on their serum uric acid levels. Inclusion criteria included isolated anterior cruciate ligament injury, complete perioperative laborato

SUBMITTER: Xuemei Z 

PROVIDER: S-EPMC12559613 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature