Adaptive Thermogenesis After Hypocaloric Low-Carbohydrate Versus Low-Fat Diets in African American Women: A Secondary Analysis.

ABSTRACT:

Objective

This secondary analysis was conducted to compare the magnitude of adaptive thermogenesis (AT) following hypocaloric low-carbohydrate (CHO) versus low-fat diets in African American (AA) women.

Methods

Sixty-nine AA women with obesity were randomized to low-CHO or low-fat hypocaloric diets for 10 weeks, followed by a 4-week weight stabilization period (all food provided). At baseline and Week 13, insulin sensitivity (S _I) was measured by intravenous glucose tolerance test, body composition by bioimpedance analysis, total energy expenditure (EE) (TEE) by doubly labeled water, and resting EE (REE) by indirect calorimetry.

Results

Forty women finished the intervention, with an average weight loss of 6.3 ± 3.9 kg and no differences between groups. AT wa

SUBMITTER: Lopez Torres SY 

PROVIDER: S-EPMC12559781 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature