Long-term risks of adverse kidney outcomes after acute kidney injury: a systematic review and meta-analysis.

ABSTRACT:

Background

Acute kidney injury (AKI) is associated with increased risks of incidence or progression of chronic kidney disease (CKD), kidney failure (KF), or major adverse kidney events (MAKE), however, it remains unclear which individuals have higher risks. Hence, we systematically reviewed the literature to explore differences in kidney dysfunction risks between AKI stages, AKI durations, and clinical settings.

Methods

We performed a systematic search in PubMed and Embase to identify studies that examined at least one outcome of interest in individuals with AKI versus without AKI, with a minimum follow-up of one year. Hazard/odds ratios (HR/OR) were pooled using random effects models. Heterogeneity across patient and disease characteristics was examined using subgroup and m

SUBMITTER: Veltkamp DMJ 

PROVIDER: S-EPMC12559794 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature