Linking the Supplementary Motor Network and Executive Function in Developing Brain.

ABSTRACT:

Objective

Essential development of the frontal lobe occurs during childhood and adolescence, affecting various executive function (EF) domains. Of the frontal areas, the supplementary motor area (SMA) located in the medial frontal cortex, is involved in various high-order EFs which include inhibition, working memory, and cognitive flexibility. However, it remains unclear how the functional network of the SMA is associated with EF development.

Methods

We assessed Wisconsin Card Sorting Test (WCST) score and resting state functional magnetic resonance imaging data from 6- to 17-year-old children and adolescents to identify age differences in SMA functional connectivity (FC) associated with EF.

Results

A total of 112 children and adolescents (62 males; mean [standard dev

SUBMITTER: Han DG 

PROVIDER: S-EPMC12559946 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature