Intrinsic Capacity Predictors of Dementia and Mortality in the Sydney Memory and Ageing Study.

ABSTRACT:

Background

Intrinsic Capacity (IC) is a developing concept focussed on promoting healthy ageing by maintaining functional abilities. It has been proposed as a better predictor of outcomes like dementia and mortality, compared to traditional frailty measures that focus on deficits. This study aims to replicate the five-factor structure of IC among older adults in Australia and to evaluate its effectiveness in predicting long-term health outcomes, in comparison with existing frailty measures.

Methods

IC scores were computed for 400 older adults aged 70 to 90 participating in the Sydney Memory and Ageing Study (MAS). Structural equation modelling, including second-order confirmatory analysis, was used to compute the five IC domains. Cox proportional hazard models were used to c

SUBMITTER: Numbers K 

PROVIDER: S-EPMC12560156 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature