Association between SHR and mortality in critically ill patients with CVD: a retrospective analysis and machine learning approach.

ABSTRACT:

Background

The stress hyperglycemia ratio (SHR), a measure of glucose metabolism, has emerged as a novel indicator of illness severity in critically ill patients. This study aims to evaluate the association between SHR and adverse outcomes in critically ill patients with cardiovascular disease (CVD).

Methods

Clinical data of 1,913 critically ill patients with CVD were extracted from the MIMIC-IV database. The primary outcomes were 360-day, 28-day, and 7-day mortality. Restricted cubic spline (RCS) regression and Cox proportional hazards models were utilized to assess the relationship between SHR and mortality risk in critically ill patients with CVD. Kaplan-Meier survival analysis was conducted to estimate survival rates across SHR quartiles. Additionally, five predictive mo

SUBMITTER: Zhou W 

PROVIDER: S-EPMC12560365 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature