The delta/alpha ratio in sleep EEG increases with the severity of depression in patients over 50 years old.

ABSTRACT:

Background

The delta/alpha ratio (DAR) of sleep electroencephalography (EEG) frequency band parameters is closely related to cognitive control in healthy adults, but its role in patients with depression over the age of 50 remains unclear. Currently, a comprehensive and reliable indicator to distinguish the severity of depression in this population is still lacking.

Methods

This study included 88 participants, all of whom underwent overnight polysomnography. Among them, 30 were in the normal control group (Hamilton Depression Rating Scale (HAMD) ≤ 8), 22 in the mild-to-moderate depression group (HAMD ≤ 35), and 36 in the severe depression group (HAMD > 35). We compared demographic characteristics, polysomnographic features, relative EEG spectral power, and their ratios among

SUBMITTER: Yang L 

PROVIDER: S-EPMC12560388 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature