Pediatric rhabdomyolysis: a systematic review and meta-analysis of etiologies, management, and outcomes.

ABSTRACT:

Background

Rhabdomyolysis is a potentially fatal disorder that occurs due to various causes. Therefore, the aim of this meta-analysis was to identify the underlying causes, evaluate the treatment options, and determine the mortality and kidney outcomes of children with rhabdomyolysis.

Methods

We comprehensively searched PubMed, Cochrane Library, Web of Science, EMBASE, and Google Scholar databases for records written in English and published until April 2025. According to PICO criteria, we included studies that enrolled pediatric patients with rhabdomyolysis and reported etiologies, treatments, mortality, and/or kidney outcomes. Subsequently, quality appraisal was conducted with Newcastle Ottawa Scale and statistical analyses were performed using comprehensive meta-analysis

SUBMITTER: Zaki HA 

PROVIDER: S-EPMC12560446 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature