Impact of community-acquired invasive Escherichia coli disease on mortality and readmissions in elderly patients: a multi-center study in Germany.

ABSTRACT:

Background

Extraintestinal pathogenic Escherichia coli (ExPEC) causes invasive E. coli disease (IED), resulting in significant morbidity and mortality, particularly among the elderly. IED can present as bacteremia or sepsis and poses serious health risks for adults aged ≥ 60 years, compounded by increasing antimicrobial resistance. However, real-world data on IED's clinical burden and risk factors in Europe are sparse. This study systematically reviews medical charts across 11 hospitals in Germany to address this gap by evaluating the impact of IED on patient outcomes, mortality rates, and hospital readmission within the elderly cohort. Through rigorous clinician review of all related medical records, we ensured accurate identification of patients with community-acquired, microbiol

SUBMITTER: Kosa F 

PROVIDER: S-EPMC12560502 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature