Evaluation of four insulin resistance surrogate indicators for predicting short-term mortality in critically ill patients with ischemic stroke: a nationwide retrospective cohort study.

ABSTRACT:

Background

Insulin resistance (IR) is closely linked to the incidence and adverse outcomes of acute ischemic stroke (IS). However, the prognostic value of various surrogate IR indices remains inconsistent across studies. This study aimed to compare the associations and discriminative abilities of four surrogate IR indices-the triglyceride-glucose index (TyG), TyG-body mass index (TyG-BMI), atherogenic index of plasma (AIP), and metabolic score for insulin resistance (METS-IR)-in relation to 28-day in-hospital mortality among critically ill patients with IS.

Methods

 This study utilized data from the eICU database to investigate critically ill patients with IS. Associations between the four IR indices and short-term mortality were assessed using multivariate regression and Co

SUBMITTER: Ouyang Q 

PROVIDER: S-EPMC12560508 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature