Treatment and risk of relapse in GCA in Western Norway 2013-2020: a retrospective cohort study.

ABSTRACT:

Objectives

During recent decades, there has been a growing recognition of the spectrum of GCA. This study aims to identify predictors of variation in the initial treatment of GCA and compare the relapse risk among patients with four different clinical phenotypes using a cohort of 256 well-defined GCA patients in Western Norway.

Methods

Regression models were used to identify predictors of differences in initial oral glucocorticoid (GC) dosage and for the administration of intravenous GC (IVGC). Tapering of GCs was analysed using a linear mixed effects model. Time to GC discontinuation, end of rheumatological follow-up, and relapse were assessed with Kaplan-Meier methods and Cox regression.

Results

Patients with cranial phenotype had lower risk of relapse, were more li

SUBMITTER: Skaug HK 

PROVIDER: S-EPMC12560782 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature