Dual-Wavelength Responsive Hydrogel Glue with Visible-Light Bonding and UV-Triggered Debonding via Ortho-Nitrobenzyl Cleavage.

ABSTRACT: Removable adhesives with controllable bonding and debonding capabilities are essential for biomedical devices, temporary fixation, and recyclable materials. Here, a dual-wavelength hydrogel glue is presented that integrates visible-light polymerization (470 nm) for strong adhesion and UV-induced degradation (365 nm) for rapid debonding. The system leverages camphorquinone as a visible-light photoinitiator and ortho-nitrobenzyl poly(ethylene glycol) dimethacrylate (ONB-PEGDMA) as a UV-cleavable crosslinker, ensuring independent control over adhesion and detachment with orthogonal polymerization and degradation. The degradation rate of ONB-PEGDMA increases proportionally with light intensity, providing precise control over cleavage kinetics, with first-order rate constants of 0.155, 0.278, a

SUBMITTER: Wang H 

PROVIDER: S-EPMC12561338 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature