Genomic Insights into an Environmental <i>Vibrio parahaemolyticus</i> Biofilm Isolate: Deciphering Alternative Resistance Mechanisms and Mobilizable Genetic Elements.

ABSTRACT:

Background/objectives

Biofilms are key in spreading antibiotic resistance in various ecosystems. This study employed comparative genomics to examine the resistance and adaptability mechanisms of the Vibrio parahaemolyticus strain Vaw-5, isolated from a seafood market biofilm.

Methods

A comparative examination of Vaw-5 and 32 publicly available V. parahaemolyticus genomes identified a distinct set of genetic resistance characteristics.

Results

Unlike clinical strains, Vaw-5 lacks acquired antimicrobial resistance genes like the blaCARB and qnr variations. Instead, its resistance potential is based on chromosomal alterations, efflux pump systems (vmeAB, vcmD), and a unique repertoire of 16 strain-specific transposons, including

SUBMITTER: Liu H 

PROVIDER: S-EPMC12561420 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature