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Promoting Re-Epithelialization in Diabetic Foot Wounds Using Integrative Therapeutic Approaches.


ABSTRACT: Background: Diabetes mellitus is a heterogeneous chronic disease with an increasing global prevalence. In Romania, 11.6% of the population is affected, yet only 6.46% receive treatment. Among diabetic patients, 15-25% develop skin lesions that may progress to ulceration and necrosis, significantly impairing quality of life and increasing the risk of complications. Methods: We conducted a prospective study including 28 patients (14 in the control group and 14 in the intervention group) with type I or II diabetes and chronic ulcers of the calf or foot (>4 cm2). The control group received standard therapy with debridement, dressings, antibiotics when indicated, and local and systemic ozone therapy. The intervention group was treated with an Integrative Therapeutic Pro

SUBMITTER: Bubulac L 

PROVIDER: S-EPMC12561719 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature