Antiviral Activity of <i>Origanum vulgare</i> ssp. <i>hirtum</i> Essential Oil-Loaded Polymeric Micelles.

ABSTRACT: Background: Encapsulating essential oils in polymer-based nanocarriers can improve their stability, solubility, and bioavailability, while maintaining the biological activity of the oil's active ingredients. In this contribution, we investigated the antiviral activity of Oregano Essential Oil (OEO) in its pure form and encapsulated into nanosized polymeric micelles, based on a poly(ethylene oxide)-block-poly(ε-caprolactone) diblock copolymer. Methods: The effect of encapsulation was evaluated using three structurally different viruses: herpes simplex virus type 1 (HSV-1) (DNA-enveloped virus), human coronavirus (HCoV OC-43) (RNA-enveloped virus), and feline calicivirus (FCV) (RNA-naked virus). The effect on the viral replicative cycle was determined using the cytopathic effec

SUBMITTER: Vilhelmova-Ilieva N 

PROVIDER: S-EPMC12561757 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature