Occurrence and Molecular Characterization of Extended-Spectrum Beta-Lactamase (ESBL)-Producing <i>Escherichia coli</i> in Broilers in Indonesia.

ABSTRACT: Extended-spectrum β-lactamase-producing Escherichia coli (ESBL-E. coli) are widespread in the food chain, but nationwide surveillance in Indonesian broiler production is limited. This study investigated the occurrence, antimicrobial resistance, phylogenetic diversity, and molecular characteristics of ESBL-E. coli from broilers in Indonesia. A total of 2182 E. coli isolates from broiler cecal samples across three regions during the period 2018-2020 were analyzed. Antimicrobial susceptibility testing and ESBL phenotyping were performed following the CLSI guidelines. ESBL resistance genes and phylogenetic groups were detected using multiplex/quadruplex PCR. ESBL-E. coli (9.9%) was most frequently observed in the western (15.2%) region, followed by the centra

SUBMITTER: Hidayatullah N 

PROVIDER: S-EPMC12561789 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature