Admission screening for extended-spectrum cephalosporin-resistant and carbapenem-resistant Enterobacterales colonization at a referral hospital in Botswana: A one-year period-prevalence survey, 2022-2023.

ABSTRACT: Extended-spectrum cephalosporin-resistant Enterobacterales (ESCrE) and carbapenem-resistant Enterobacterales (CRE) are significant contributors to infection-related mortality in low- and middle-income countries. Colonization with ESCrE and/or CRE can precede infection and serve as a reservoir for transmission within healthcare facilities and the community.We conducted a 12-month period-prevalence study, screening patients for ESCrE and CRE upon admission to a referral tertiary hospital Emergency Department in Botswana. Rectal swabs were collected within 24 hours of hospital arrival. Colonization was identified using selective culture media and confirmed using automated susceptibility testing. Associations between ESCrE/CRE colonization, and clinical and demographic variables were analysed

SUBMITTER: Zankere T 

PROVIDER: S-EPMC12561989 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature