Multi-Omics Analysis and Comparison of the Developmental Characteristics of Muscle Fiber Types Between Huainan and Large White Pigs in Early Postnatal Period.

ABSTRACT: To investigate the molecular mechanisms underlying muscle fiber development in different pig breeds and their impact on meat quality, this study collected the longissimus dorsi muscle of the indigenous Huainan pig and the commercial Large White pig at four developmental stages (0, 7, 14, and 21 days postnatal). Muscle fiber types were identified using myosin ATPase staining, while transcriptomics and non-targeted metabolomics were employed to analyze differences in gene expression and metabolite composition. The results showed that the Huainan pig had a higher proportion of oxidative muscle fibers, indicating superior aerobic metabolic capacity and meat quality. Transcriptome data identified 18 differentially expressed genes common to both pig breeds, including KLF4, NOS1,

SUBMITTER: Wang J 

PROVIDER: S-EPMC12562198 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature