Impact of UV Exposure and Incidence of Merkel Cell Carcinoma Between 1990 and 2018 in Austria.

ABSTRACT:

Background

The purpose of this study was to report on (i) patients' demographics and (ii) Austrian UV data, and (iii) to examine a possible association between UV exposure and the onset of disease in Austria between 1990 and 2018.

Methods

We included all patients diagnosed with MCC and their clinical and demographic data to compare with UV radiation.

Results

A total of 538 cases were identified, and the incidence (per 100,000/y) increased from 0.013 to 0.43. The MCC incidence was significantly higher in West Austria (mean incidence 0.269 ± 0.04) compared to East Austria (0.180 ± 0.02 p = 0.005). Notably, the mean and maximum UV radiation values were higher in the western (p < 0.001) compared to the eastern part of Austria. The sum (p = 0.033; r: 0

SUBMITTER: Erovic BM 

PROVIDER: S-EPMC12562544 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature