Red-Wine Gene Networks Linked to Exceptional Longevity in Humans.

ABSTRACT: Despite the health concerns regarding alcohol and its link to cancer, moderate consumption of red wine has been associated with healthy aging and longevity, defined as up to one drink per day for women and two drinks per day for men (approximately 142 mL or 5 oz per drink). Previous research has revealed the health benefits of red wine, particularly in relation to cardiovascular disease. However, the influence of genetic factors on these benefits remains to be elucidated. In this study, we explored genes linked to red wine and created a curated gene set that intersects with those related to centenarians, which are markers of exceptional longevity. By analyzing literature from over 190 databases, we identified and validated a curated list of 43 genes associated with red wine and centenarian

SUBMITTER: Lacayo P 

PROVIDER: S-EPMC12562682 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature