OCTA Biomarkers Underlying Structure-Function Correlations in Idiopathic Epiretinal Membrane: A Systematic Review.

ABSTRACT: Background: Idiopathic epiretinal membrane (iERM) is a common retinal pathology in elderly patients, thought to originate primarily from an anomalous process of posterior vitreous detachment. The standard treatment is pars plana vitrectomy (PPV) with membrane peeling. No consensus exists regarding the optimal timing of surgery, nor is it clear which patients are most likely to benefit. Given that iERM profoundly affects retinal vascular morphology and function, optical coherence tomography angiography (OCTA) has emerged as a valuable tool for identifying potential biomarkers. This systematic review aimed to synthesize the available evidence on OCTA-derived biomarkers and their correlations with visual function before and/or after surgical intervention in iERM, with a particular focu

SUBMITTER: Sere AM 

PROVIDER: S-EPMC12562888 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature