Impact of Red Pack Cell Transfusion Before or After Endoscopy on Mortality in Patients with Upper Gastrointestinal Bleeding: A Multicenter Cohort Study.

ABSTRACT:

Background

The impact of transfusion timing relative to endoscopy in upper gastrointestinal bleeding (UGIB) remains unclear.

Aim

To assess whether transfusion performed before versus after endoscopy affects 30-day mortality in UGIB.

Methods

We conducted a post hoc analysis of a multicenter cohort study including 3324 UGIB patients consecutively admitted in hospital. Propensity score matching adjusted for clinical and procedural variables.

Results

Among 2017 transfused patients, 34.7% received Red Blood Cells (RBC) before endoscopy. Patients who received transfusions before endoscopy were older, had more severe comorbidities, and presented with a worse physical and hemodynamic status. This study also explored whether transfusion timing relative to endoscopy affe

SUBMITTER: Marmo C 

PROVIDER: S-EPMC12563327 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature