Diagnostic Accuracy of Coronary CT Angiography in Ruling Out Significant Coronary Artery Disease in Candidates for Transcatheter Aortic Valve Replacement.

ABSTRACT: Obstructive coronary artery disease (CAD) is common in patients undergoing transcatheter aortic valve implantation (TAVI). While invasive coronary angiography (ICA) is the gold standard for coronary evaluation, coronary computed tomography angiography (cCTA) is gaining interest for its potential to exclude obstructive CAD during pre-procedural imaging. This study aimed to assess the diagnostic accuracy of cCTA in ruling out significant CAD in TAVI candidates. We retrospectively analyzed 95 TAVI candidates (mean age 77.7 ± 8.5 years) who underwent both cCTA and ICA. Diagnostic performance of cCTA-sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy-was assessed using ICA as the reference, in both patient- and vessel-based models. Obstructi

SUBMITTER: Gallo C 

PROVIDER: S-EPMC12564097 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature