Application of BRAFO-Tiered Approach for Risk-Benefit Assessment of Nut Consumption in Chinese Adults.

ABSTRACT: Nuts are nutrient-rich foods that help reduce the risk of coronary heart disease (CHD), but their potential contamination with aflatoxins (AFs) may increase the risk of liver cancer. In this study, the European Benefit-Risk Analysis for Foods (BRAFO) framework was used to evaluate both the health risks and benefits of nut consumption among Chinese adults. Based on the actual consumption patterns of nuts among the Chinese population, the current consumption level was set as the reference scenario (4.66 g/day), and three alternative scenarios were simulated with a daily nut consumption of 10, 20, and 30 g, respectively. Dose-response relationships were established using a two-stage dose-response analysis for nut consumption and CHD risk, and a one-stage dose-response analysis for aflatoxin B

SUBMITTER: Liu Z 

PROVIDER: S-EPMC12564558 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature