Impact of Computed Tomography-Defined Osteopenia on Outcomes of Transcatheter Aortic Valve Implantation: A Single-Center Retrospective Study.

ABSTRACT: Background/Objectives: Transcatheter aortic valve implantation (TAVI) is a standard treatment for severe aortic stenosis, especially in older adults and high-risk patients. However, many TAVI candidates have osteopenia or osteoporosis, indicated by low bone mineral density (BMD), which is linked to frailty and adverse outcomes. Although prior research suggests an association with poor clinical outcomes, data remain limited. We investigated the impact of osteopenia on TAVI outcomes, hypothesizing that a lower BMD is associated with poor perioperative outcomes and decreased long-term survival. Methods: In this single-center retrospective study, we analyzed data from 411 patients who underwent TAVI at Yamaguchi University Hospital from 2014 to 2024. Clinical and survival data we

SUBMITTER: Kurazumi H 

PROVIDER: S-EPMC12564642 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature