Outcomes of Living-Donor Liver Transplantation for Cholangiocarcinoma Versus Hepatocellular Carcinoma in the United States.

ABSTRACT: Objectives: Cholangiocarcinoma (CCA) is a malignancy of the biliary epithelium associated with high mortality. Hepatocellular carcinoma (HCC) is the most common primary liver tumor and has an established indication for liver transplant (LT). Living-donor LT (LDLT) may offer a curative and timely option for selected CCA patients. Methods: The United Network of Organ Sharing/Organ Procurement and Transplantation Network (UNOS/OPTN) data was reviewed from January 2010 to December 2022 for patients who underwent LDLT with HCC or CCA diagnostic codes. Post-LDLT survival for CCA was compared to HCC and non-HCC/CCA patients using Kaplan-Meier analysis. Stepwise multivariate analysis adjusted for recipient age, gender, race, and underlying etiology. Results: LDLT for CCA was m

SUBMITTER: Gurakar M 

PROVIDER: S-EPMC12565021 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature