Bridging Breeds: Transcriptomic Insights into Immune Traits of Yili, Thoroughbred, and Kazakh Horses.

ABSTRACT:

Background

Studying the genetic characteristics and molecular mechanisms of immune regulation in horses is of great significance for protecting their genetic resources, improving breeding strategies, and enhancing their disease resistance, thereby ensuring their healthy performance in both sports and production.

Aims/objectives

This study investigates the genetic characteristics and molecular mechanisms underlying immune regulation in Yili horses, comparing them with Thoroughbreds and Kazakh horses.

Methods

Blood samples from each breed were analyzed for physiological, biochemical, and immune indices alongside transcriptome sequencing to identify differentially expressed genes (DEGs).

Results

The results revealed significant differences in neutrophil counts, mo

SUBMITTER: Wang T 

PROVIDER: S-EPMC12565139 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature