The Cytochrome P450 Enzyme SsCyp64 Mediates γ-linolenyl Alcohol in Regulating Sexual Mating/Filamentation and Pathogenicity of <i>Sporisorium scitamineum</i>.

ABSTRACT: Sugarcane smut, caused by Sporisorium scitamineum, is a devastating fungal disease of sugarcane. Sexual mating/filamentation of opposite mating types is a key step in the infection and pathogenicity of S. scitamineum, yet its regulation remains unclear. In this study, we identified a cytochrome P450 enzyme-encoding gene, SsCYP64, which plays an important role in oxidative stress and maintaining cell membrane stability in S. scitamineum. Further investigations revealed that deletion of SsCYP64 leads to a decrease in the transcriptional level of SsPRF1, a key transcription factor regulating the sexual mating of S. scitamineum. Subsequently, the constitutive expression of SsPRF1 restored the defect in sexual mating/filamentation of the <

SUBMITTER: Cai E 

PROVIDER: S-EPMC12565241 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature