Induction of Extrinsic Apoptotic Pathway in Pancreatic Cancer Cells by <i>Apteranthes europaea</i> Root Extract.

ABSTRACT: Pancreatic cancer is an extremely deadly disease with few effective treatment options and the lowest survival rate among all types of cancer. As a result, there is an urgent need for the development of new and more effective treatment strategies. Natural products have long been a vital source of drug discovery, offering unique bioactive compounds, and representing a promising source for new, effective, and less toxic treatments. In the present study, we aimed to investigate the effects of Apteranthes europaea (Guss.) Murb (A. europaea) root extract on the growth of pancreatic cancer cells. The proliferation assay (XTT) and real-time analysis using the IncuCyte Live-Cell Analysis System, following treatment of PL45 and Mia PaCa-2 pancreatic cancer cells with escalating concent

SUBMITTER: Bar-Shalom R 

PROVIDER: S-EPMC12565304 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature