Analysis of Amino Acid and Derivative Diversity and Antioxidant Capacity in <i>Ophiocordyceps sinensis</i> and Its Substitutes.

ABSTRACT: In this study, we used liquid chromatography-tandem mass spectrometry (LC-MS/MS) combined with multivariate statistical analysis to conduct comprehensive qualitative and quantitative profiling of amino acids and their derivatives in wild Ophiocordyceps sinensis (O. sinensis) samples from Naqu (NQ) and Xiaojin (XJ), cultivated O. sinensis (RG), and Bailing Capsules (BL). The objective was to systematically characterize amino acid metabolism and assess its correlation with antioxidant functionality. A total of 82 amino acids and their derivatives were identified. XJ had the highest essential amino acids, while BL had significantly lower content (except lysine) (p < 0.05). Antioxidant assays revealed that NQ and XJ samples exhibited superior antioxidant activity in

SUBMITTER: Tang H 

PROVIDER: S-EPMC12565307 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature