Insights into the Mycosphere Fungal Community and Its Association with Nucleoside Accumulation in <i>Ophiocordyceps sinensis</i>.

ABSTRACT: Soil microbiomes are critical environmental factors influencing the occurrence and quality formation of Ophiocordyceps sinensis, a valuable medicinal fungus endemic to the Qinghai-Tibet Plateau. However, few studies have explored the relationship between mycosphere soil fungal communities and the quality characteristics of O. sinensis. This research aimed to systematically analyze the structural characteristics and diversity of fungal communities in mycosphere soils of O. sinensis from eight geographical regions using Illumina high-throughput sequencing, and compare the nucleoside contents in O. sinensis from the corresponding sites. Alpha diversity indices showed that soil samples from Yushu and Guoluo in Qinghai Province exhibited higher fungal richness and di

SUBMITTER: Zhang J 

PROVIDER: S-EPMC12565341 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature