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Impact of Serum Uric Acid Levels on the Diagnosis of Coronary Vasospastic Angina.


ABSTRACT: Background: Given that insulin resistance and lower levels of high-density lipoprotein cholesterol are reportedly associated with the development of coronary vasospasm, metabolic disorders may play a significant role in the underlying mechanisms of vasospastic angina (VSA). In this context, however, the impact of serum uric acid (SUA) levels on the diagnosis of VSA remains unclear. Methods: From May 2012 to March 2025, a total of 947 patients undergoing intracoronary acetylcholine (ACh) provocation tests for diagnosing VSA were included. Positive diagnosis of ACh provocation testing was defined as angiographic coronary spasm accompanied by chest symptoms and/or ischemic electrocardiographic changes. The primary interest of this study was to evaluate the potential relationship

SUBMITTER: Tamura N 

PROVIDER: S-EPMC12565358 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature