High-Fidelity MicroCT Reconstructions of Cardiac Devices Enable Patient-Specific Simulation for Structural Heart Interventions.

ABSTRACT: Background/Objective: Precise preprocedural planning is essential for the safety and efficacy of structural heart interventions. Conventional imaging modalities, while informative, do not allow for direct and accurate visualization, limiting procedural predictability. We aimed to develop and validate a high-resolution micro-computed tomography (microCT)-based reverse modeling workflow that integrates digital reconstructions of metallic cardiac devices into patient imaging datasets, enabling accurate, patient-specific virtual simulation for procedural planning. Methods: Clinical-grade transcatheter heart valves, septal defect occluders, patent ductus arteriosus occluders, left atrial appendage closure devices, and coronary stents were scanned using microCT (36.9 μm resolution)

SUBMITTER: Zhu Z 

PROVIDER: S-EPMC12565625 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature