Association Between Hyponatremia and Mortality and Readmission in Multimorbid Older Adults-A Cohort Study.

ABSTRACT: Background/Objectives: Hyponatremia has been associated with mortality and hospital readmissions. Although multimorbid older patients are particularly affected, specific data on this group are lacking. Methods: A prospective cohort was used based on the OPERAM (OPtimising thERapy to prevent Avoidable hospital admissions in the Multimorbid elderly) trial, a European multicenter, cluster-randomized trial among hospitalized patients aged ≥70 years with ≥3 chronic medical conditions taking ≥5 long-term medications, with documented sodium values at admission, excluding participants with hypernatremia (>145 mmol/L). The primary outcome was all-cause 1-year mortality, and secondary outcomes were 30-day mortality and readmission at 1 year and at 30 days. We examined the association b

SUBMITTER: Netzer S 

PROVIDER: S-EPMC12565651 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature