Risk of Osteoporosis-Related Fracture in Children and Adolescents with Intellectual Disability.

ABSTRACT: Background and Objectives: Children and adolescents with intellectual disability (ID) experience substantial health disparities, yet their skeletal health has been overlooked. Early-onset osteoporosis and fracture remain underrecognized in this population. Hence, this study assessed the risk of osteoporosis with concomitant fracture in this population using nationwide cohort data. Materials and Methods: This population-based retrospective cohort study examined data from South Korea's National Health Insurance Service-National Health Information Database (2004-2021). In all, 75,790 individuals with ID and 922,921 control individuals aged 2-18 years were included. The primary outcome was osteoporosis with concomitant fracture occurring within 1 year before or after the osteopor

SUBMITTER: Yoo JR 

PROVIDER: S-EPMC12566074 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature