Acute Kidney Injury Biomarkers in Marathon Runners: Systematic Review and Meta-Analysis.

ABSTRACT: Background and Objectives: The objectives of this review were as follows: to measure changes in renal biomarker levels before, immediately after, and 24 h post-marathon; to identify promising biomarkers for the diagnosis of acute kidney injury; and to describe the temporal patterns of biomarker dynamics in relation to the marathon. Materials and Methods: Studies of marathon runners reporting AKI-related biomarkers were included. Four databases (PubMed, EMBASE, Web of Science, and LILACS) were searched. Data on study design, participant characteristics, and biomarker values (pre-, post-, and 24 h post-race) were extracted, and a random effects meta-analysis was performed. Risk of bias was assessed with the National Heart, Lung, and Blood Institute pre-post tool. Results

SUBMITTER: Leucuta DC 

PROVIDER: S-EPMC12566084 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature