<i>Eleutherococcus senticosus</i> Fruit Extract Stimulates the Membrane Potential of the Trachea and Small Intestine in Rabbits.

ABSTRACT:

Background

Eleutherococcus senticosus (Rupr. et Maxim.) Maxim., widely used in Russian and Chinese traditional medicine for its anti-inflammatory activity, contains bioactive compounds capable of stabilizing epithelial function and reducing inflammation. Despite prior research on its effects in the colon, the impact and mechanism of action of E. senticosus fruit extract on epithelial tissues of the upper digestive and respiratory tract remains unexplored.

Objectives

This study aimed to evaluate the influence of E. senticosus fruit extract on the transepithelial electrical potential and resistance in the tracheal and small intestinal epithelium of rabbits. In addition, the chemical composition of the extract was also profiled by the means of UHPLC-DAD-MS.

SUBMITTER: Graczyk F 

PROVIDER: S-EPMC12566354 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature