Unlocking the Potential of <i>vB</i>_<i>EfaS</i>_<i>LOK1</i>: A Newly Isolated Bacteriophage Against <i>Enterococcus faecalis</i>.

ABSTRACT: Phage therapy has emerged as a promising alternative for combating infections caused by drug-resistant pathogens. Among these, Enterococcus faecalis remains a significant public health concern due to its persistence in clinical settings and frequent involvement in healthcare-associated infections (HAIs). In this study, we report the characterization of the lytic bacteriophage vB_EfaS_LOK1, isolated from urban sewage using E. faecalis strain IIH-74.4 as the host. Transmission electron microscopy revealed morphological features consistent with the phages formerly classified within the Siphoviridae family. The phage exhibited high thermal and pH stability, remaining viable up to 70 °C and within a pH range of 4-11. It displayed a latent period of 20 min and a burst

SUBMITTER: Plata Suarez LM 

PROVIDER: S-EPMC12566377 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature