Targeted Chemical Profiling and Dereplication of Australian Plants of the Family Haemodoraceae Using a Combined HPLC-MS and HRLC(ESI)-MS Approach.

ABSTRACT: Australian plants of the family Haemodoraceae have been a reliable source of new secondary metabolites, particularly those of the 'phenylphenalenone' class, and related chromenes and xanthones. Some of these compounds demonstrate anti-microbial properties against both Gram-negative and Gram-positive bacteria. Chemical profiling of thirty individual ethanolic extracts from six separate species of Australian plants belonging to the family Haemodoraceae was conducted using an HPLC-MS approach reinforced by HRLC(ESI)-MS. Six of the extracts were further explored by employing HRLC(ESI)-MS and the compounds present were characterised and confirmed based on a comparison to the original data. All thirty extracts were assessed for biological activity against the parasitic nematode Haemonchus con

SUBMITTER: Thompson L 

PROVIDER: S-EPMC12566560 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature