Interaction Between First-Trimester Energy-Adjusted Dietary Inflammatory Index and Educational Level on the Risk of Anemia During the Second and Third Trimesters: A Prospective Cohort Study.

ABSTRACT: Objectives: The aim of this cohort study was to assess the associations of first-trimester energy-adjusted Dietary Inflammatory Index (E-DII) and maternal educational level with anemia during the second and third trimesters, as well as their potential interactions. Methods: This study enrolled 562 eligible pregnant women. Multivariable modified Poisson regression with robust variance was used to assess the associations of first-trimester E-DII and maternal educational level with anemia during the second and third trimesters. Restricted cubic splines (RCS) explored nonlinear associations, while additive and multiplicative interaction models evaluated the interaction between first-trimester E-DII and maternal education. Results: The participants, with a mean age of 29.45

SUBMITTER: Xia F 

PROVIDER: S-EPMC12566625 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature