Protein-Based Electrospun Nanofibers Doped with Selenium Nanoparticles for Wound Repair.

ABSTRACT: Background/Objectives: The design of scaffolds that mimic the extracellular matrix has gained increasing attention in regenerative medicine. This study aims to develop and characterize electrospun nanofibrous scaffolds based on pullulan blended with either gelatin or gliadin and doped with selenium nanoparticles (Se NPs), to assess the influence of protein type and Se NP doping on scaffold performance and regenerative potential. Methods: Se NPs were synthesized via redox reaction and stabilized using pullulan. Electrospun scaffolds were then prepared by blending pullulan-stabilized Se NPs with either gelatin or gliadin. The resulting fibers were characterized using a multidisciplinary approach, including physicochemical (morphology, fiber dimension, swelling capacity, surface

SUBMITTER: Ruggeri M 

PROVIDER: S-EPMC12566627 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature