Impact of Nutritional Status on Severe Radiation-Induced Mucositis in Oropharyngeal Cancer Patients Undergoing Chemo-Radiotherapy.

ABSTRACT: Background/Objectives: Severe radiation-induced mucositis (RIM) is the most distressing acute side effect experienced by oropharyngeal squamous cell carcinoma (OPSCC) patients during chemo-radiotherapy (CRT), with a prevalence between 40 and 68%. RIM severity exhibits a multifactorial etiology that remains unclear. We aimed to analyze nutritional and morphofunctional predictive factors for severe RIM in OPSCC patients undergoing CRT. Methods: A prospective cohort study was conducted. Global Leadership Initiative on Malnutrition (GLIM) criteria, bioelectrical impedance vector analysis (BIVA), functional assessment and dosimetric analysis were performed prior to radiotherapy. Results: Eighty-two patients were analyzed. Severe RIM affected 46.3% of patients. Severe malnut

SUBMITTER: Fernandez-Forne A 

PROVIDER: S-EPMC12566891 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature