The Risk Factor Analysis of Gallbladder Gangrene in Acute Acalculous Cholecystitis: A Single-Center Retrospective Study.

ABSTRACT:

Objective

This research was performed to determine the risk factors for gallbladder gangrene in acute acalculous cholecystitis patients and to assess the predictive ability of inflammatory markers.

Methods

The study included 226 acute acalculous cholecystitis patients who underwent laparoscopic cholecystectomy within 72 h of onset. The receiver operating characteristic curves were employed to determine the optimal cut-off, specificity, and sensitivity of inflammatory markers in predicting gangrenous cholecystitis. Logistic regression analysis was conducted to ascertain the independent risk factors associated with gallbladder gangrene.

Results

The incidence rate of gallbladder gangrene in acute acalculous cholecystitis was 45.1% (102/226). Compared with other inflammat

SUBMITTER: Zheng JL 

PROVIDER: S-EPMC12566959 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature