The Neuroanatomical Correlates of Bladder Filling: An Activation Likelihood Estimation Meta-Analysis of Functional Neuroimaging Studies.

ABSTRACT:

Background

Urinary continence relies on a complex interplay between urine storage and voiding involving both spinal reflex circuits and supraspinal brain areas to coordinate volun-tary control over emptying. Despite a vast number of studies on the pathophysiology of neurogenic bladder and urge incontinence, less is known about the central correlates of bladder filling.

Methods

An ALE (activation likelihood estimation) meta-analysis including a total count of 14 studies investigating 243 participants under different conditions of bladder filling during functional neuroimaging was performed to demonstrate the neuroanatomical correlates of bladder filling. The literature search and reporting were conducted according to the PRISMA-P 2020 guideline. Data analysis was performed us

SUBMITTER: Muller C 

PROVIDER: S-EPMC12567025 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature