Structural and Functional Enhancement of Halal Gelatin Capsules Reinforced with Corn Husk Cellulose.

ABSTRACT: Corn husk-derived cellulose (CHC) was incorporated into gelatin-cassava starch (CS) capsule formulations to evaluate its effectiveness as a sustainable reinforcing agent. The addition of CHC enhanced the structural cohesion of the films and improved their resistance to storage-related temperature-humidity stress, while maintaining desirable flexibility. Consistent with this, the films retained mechanical performance and appearance under ICH-aligned storage conditions, indicating better endurance during storage and processing. Disintegration performance remained within pharmacopeial requirements in both acidic and neutral media, confirming the suitability of the capsules for oral delivery applications. Surface assessment revealed more uniform morphology and fewer irregularities in the capsu

SUBMITTER: Firdaus FE 

PROVIDER: S-EPMC12567270 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature