Anticancer Activity of Snake Venom Against Breast Cancer: A Scoping Review.

ABSTRACT: Breast cancer remains a leading cause of cancer-related mortality worldwide, necessitating innovative therapeutic approaches. This scoping review summarizes experimental evidence on the anticancer activity of snake venom and its bioactive components against breast cancer, drawing from a variety of in vitro and in vivo studies. Aimed at critically evaluating the therapeutic potential and underlying mechanisms, this review consolidates findings on venoms from multiple snake species, including both crude preparations and purified proteins or peptides, revealing a diversity of mechanisms of action. Reported effects include induction of apoptosis, generation of reactive oxygen species, disruption of cell membrane integrity, inhibition of cell proliferation and metastasis, and modulation of onco

SUBMITTER: Kim EJ 

PROVIDER: S-EPMC12567882 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature