Simultaneous Occurrence of Field Epidemics of Rabbit Hemorrhagic Disease (RHD) in Poland Due to the Co-Presence of <i>Lagovirus europaeus</i> GI.1 (RHDV)/GI.1a (RHDVa) and GI.2 (RHDV2) Genotypes.

ABSTRACT: The highly fatal rabbit hemorrhagic disease (RHD) that first emerged in 1984 in China has spread worldwide and affects both domestic and wild rabbits. The disease was originally caused by RHD virus (Lagovirus europaeus, L.europaeus) of GI.1 genotype, but over the years, two further pathogenic forms, known as the antigenic and genetic variant RHDVa (GI.1a) and RHDV2 (genotype GI.2), have been identified. RHD was first reported in Poland in 1988, when two RHDV strains were isolated, currently classified as GI.1c, while RHDVa and RHDV2 emerged in 2003 and 2016, respectively. In this study, using virological and molecular methods, we characterized five new RHDV strains belonging to GI.1 (RHDV)/GI.1a (RHDVa) and GI.2 (RHDV2) genotypes isolated in Poland in 2020-2022, in domestic rabbits

SUBMITTER: Fitzner A 

PROVIDER: S-EPMC12568209 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature