Association of Exposure to Phthalate Metabolites with Antenatal Depression in US Pregnant Women.

ABSTRACT: Antenatal depression affects 10-20% of pregnant women, with notable adverse outcomes for the neonates. Limited studies have indicated a potential link between exposure to phthalate metabolites and depression. The association between phthalate metabolites and depression in pregnant women is unknown. We sought to evaluate the association of exposure to phthalate metabolites with depression severity score in US pregnant women. This cross-sectional study used data collected by the National Health and Nutrition Examination Survey during 2005-2018 on pregnant adults who completed urinary profiles that examined 12 common phthalate metabolites. Linear and quantile sum regressions were used to evaluate the association between depressive symptoms (measured by the Patient Health Questionnaire, PHQ-9)

SUBMITTER: Dubey P 

PROVIDER: S-EPMC12568236 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature